bt365在线投注特邀学术报告
Subject: Autophagy functions as an antiviral mechanism against geminiviruses in plants
Speaker: Yakupjan Haxim
Host: Prof. Yinyue Deng
Time: 15:00-16:00 May 15 (Monday)
Location: Science Building Room 317(资环学院科技楼317室)
Yakupjan Haxim has completed his postgraduate research in Xinjiang University, and has been done his doctoral research which about antiviral mechanism of plant autoph
agic machinery against geminivirus from 2012 to present in Tsinghua University. During his doctoral research ,he has made some progress which also has been published in
Elife. He will share this with us more in his lecture.
Yakupjan et al. show that autophagy helps to protect plants against three geminiviruses. βC1 protein from Cotton leaf curl Multan virus (CLCuMuV) interacts with a plant protein called ATG8 and is then sent to be broken down by autophagy. Further experiments then identified a mutation in this protein that stopped it interacting with ATG8. Viruses carrying this mutated form of βC1 caused more severe symptoms and replicated more in N. benthamiana plants.
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Guangdong Innovative and Entrepreneurial Research Team of
Sociomicrobiology Basic Science and Frontier Technology